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Innovation Creates the Future

Self-developed Pet Cat Vaccine: Miao Yi Duo—Feline PanleukoPenia, Calicivirosis, Rhinotracheitis Vaccine, Inactivated (Strain 708+ Strain 60+ Strain 64)

2024.08.24

Prevention is better than cure. Vaccinate your cat with a triple vaccine to protect your cat's health.

Pulike's subsidiary Huizhong Animal Health has independently developed the domestically produced triple inactivated cat vaccine, Meow Yi Duo (Feline PanleukoPenia, Calicivirosis, Rhinotracheitis Vaccine, Inactivated (Strain 708+ Strain 60+ Strain 64), which was approved by the Ministry of Agriculture and Rural Affairs on April 16, 2024 (Approval number for veterinary products: Veterinary Medicine Linzi 160026076). Meow Yi Duo is the seedling of dreams that all people yearn for. At the beginning of the project, we set a goal: to make a high-quality triple vaccine for cats with high safety and good immune effects. Meow Yi Duo has obvious advantages. Let us unveil its mystery together.

Technical Feature

01 Preferred strains prevalent in China

Through gene evolution tree analysis and checkerboard cross-neutralization test, the prevalent strains were systematically screened to obtain highly immunogenic strains that induce broad-spectrum neutralizing antibody responses, which have better immune response and protection against locally prevalent feline herpesvirus and feline calicivirus.

Selection of highly immunogenic strains from 71 FCV strains by checkerboard cross-neutralisation test
The gD protein of the imported FHV strain differed in several ways from the gD protein concept of the China epdemic strain.

02 Optimal Antigen Formulation

High-throughput configurations screen for optimal 3-antigen ratios to unleash maximum immune efficacy. Enhance the strength of the immune response to improve the effectiveness and stability of immunity.

03 Self-proprietary enhancers

•Enhancement of immune response: a new type of potent adjuvant with both humoral and cellular immunity, high response and rapid antibody production.

•Enhanced vaccine efficacy: Increase the efficacy of the product by increasing the immune response and persistence, effectively preventing infections.

Feature

Two-dose optimum immunity High efficient protection

•Selection of local epdemic strains: Through phylogenetic tree analysis and a checkerboard approach to screen domestic prevalent strains, there is a superior immune response and protection against feline herpesvirus and feline calicivirus.

•Unique antigenic formulation: Delivers maximal immunogenicity to enhance immune protection.

•Patented novel adjuvant: A new type of adjuvant that enhances both humoral and cellular immunity, provoking a strong response and rapid antibody production.

Safe and hypoallergenic, Pain-free and scar-free

•Chromatographic purification process: Highly efficient biological separation and purification remove impurities from suspension cultures, enhancing the vaccine's effective antigen content and purity.

•Extremely low endotoxin levels: <5 EU per dose.

•Patented novel adjuvant: Post-vaccination in cats results in no adverse reactions, pain-free and without scarring.

 Longer shelf life Consistent batch quality

•Extra-long shelf life: Provides protection for 27 months.

•Whole suspension culture process: Large-scale, fully automated, and enclosed production lines ensure consistent quality between batches.

Clinical Experiments

28,000 high-quality vaccines were used in clinical bridging trials in 19 provinces. After immunization, cats of different breeds and ages had normal mental state and appetite, no palpation pain, no nodules, and no allergic reactions at the injection site. The antibodies in the cats' bodies reached the level of immune protection, which fully proves that the Miao Yiduo vaccine is effective and safe.

Immunization and Deworming Program

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